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Report from the Faculty of Family Planning and Reproductive Health Care AGM, May 2003: Medical termination of pregnancy in the late first trimester
  1. P Stewart, FRCOG, Consultant Obstetrician and Gynaecologist1,
  2. J Fletcher, RN, MA, Clinical Nurse Specialist1 and
  3. A Sharma, MRCOG, Consultant in Family Planning and Reproductive Health Care2
  1. Royal Hallamshire Hospital, Sheffield, UK
  2. Central Health Clinic, Sheffield, UK
  1. Correspondence Mr P Stewart, Department of Obstetrics and Gynaecology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK. E-mail: rpeter.stewart{at}


In the UK, mifepristone and gemeprost are licensed for medical termination of pregnancy (TOP) in the first trimester up to 63 days' amenorrhoea. Current practice, however, is to use low-dose (200 mg) mifepristone and misoprostol. We report a large cohort study using these drugs for medical TOP in the first trimester after 63 days amenorrhoea. Of 415 patients undergoing the procedure, 392 (95%) aborted completely and 96% required only two doses of misoprostol. We conclude that the regime is effective with few complications, however certain safeguards may be necessary for its widespread introduction

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