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FFPRHC Guidance (April 2005) Drug interactions with hormonal contraception


This Guidance provides information for clinicians and women using hormonal contraception applicable when concurrent medications are prescribed. Akey to the grades of recommendations, based on levels of evidence, is given at the end of this document. Details of the methods used by the Clinical Effectiveness Unit (CEU) in developing this Guidance and evidence tables summarising the research basis of the recommendations are available on the Faculty website ( Abbreviations (in alphabetical order) used include: CEU, Clinical Effectiveness Unit; COC, combined oral contraceptive/contraception; DMPA, depot medroxyprogesterone acetate; EE, ethinylestradiol; ENG, etonorgestrel; IUD, copper-bearing intrauterine contraceptive device; LNG, levonorgestrel; LNG-IUS, levonorgestrel-releasing intrauterine system; POC, progestogen-only contraceptive/contraception; POP, progestogen-only pill; SJW, St John's Wort; WHO, World Health Organization; WHOMEC, WHO Medical Eligibility Criteria for Contraceptive Use; WHOSPR, WHO Selected Practice Recommendations for Contraceptive Use.

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