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There were undisclosed conflicts of interest (COI) for one of the authors. She has provided the following COI statement: “VJ is an inventor of the patented CycleBeads technology, owned by Georgetown University, that is the subject of this research. VJ is related to the owner of Cycle Technologies, which has an exclusive license from Georgetown University for commercialization of the technology. VJ has no financial relationship to and receives no income from Cycle Technologies. Neither she nor the other authors receive, nor will they receive, royalties related to the licensed technology”.