Differences in risk and preventive behaviours amongst human papillomavirus-vaccinated and unvaccinated women adjusted for vaccination cohort
| Variable | n | Vaccinated % (n) | Unvaccinated % (n) | Adjusted OR* (95% CI) | p |
|---|---|---|---|---|---|
| Sexual behaviour | |||||
| Aged ≤15 years at first intercourse | 336 | 61.8 (139/225) | 53.2 (59/111) | 0.98 (0.60–1.60) | 0.93 |
| Condom use at first intercourse | 336 | 76.4 (172/225) | 69.4 (77/111) | 0.55 (0.32–0.96) | 0.036 |
| Condom use at last intercourse | 298 | 25.9 (52/201) | 22.7 (22/97) | 0.85 (0.47–1.60) | 0.61 |
| Non-regular partner and no condom used at last intercourse | 297 | 22.9 (46/201) | 21.9 (21/96) | 1.1 (0.57–2.08) | 0.72 |
| Last sexual contact included anal intercourse | 322 | 2.3 (5/218) | 8.7 (9/104) | 4.34 (1.23–14.29) | 0.022 |
| Used drugs/alcohol at last intercourse | 234 | 24.4 (38/156) | 25.6 (20/78) | 0.91 (0.47–7.75) | 0.78 |
| Last sexual contact regular partner | 337 | 73.6 (167/227) | 70.9 (78/110) | 0.79 (0.46–1.35) | 0.39 |
| 3+ partners in last 6 months | 300 | 13.3 (27/203) | 22.7 (22/97) | 2.12 (1.08–4.17) | 0.031 |
| 6+ lifetime partners | 288 | 28.0 (54/193) | 37.9 (36/95) | 1.25 (0.71–2.17) | 0.42 |
| Emergency contraception use in last year | 337 | 36.7 (83/226) | 26.1 (29/111) | 0.63 (0.37–1.10) | 0.080 |
| Emergency contraception use over lifetime | 269 | 60.7 (111/183) | 57.0 (49/86) | 0.72 (0.41–1.28) | 0.27 |
| Had sex abroad | 330 | 8.2 (18/220) | 9.1 (10/110) | 1.08 (0.46–2.56) | 0.86 |
| Clinical history/STI diagnosis | |||||
| Ever had termination | 311 | 7.7 (16/207) | 8.7 (9/104) | 0.92 (0.38–2.22) | 0.85 |
| Received previous treatment for STI | 345 | 21.6 (50/231) | 28.1 (32/114) | 1.18 (0.68–2.04) | 0.55 |
| Tested for Chlamydia trachomatis outside GUM | 324 | 64.5 (140/217) | 71.0 (76/107) | 1.11 (0.63–1.96) | 0.70 |
| STI diagnosis from clinic visit | 342 | 35.7 (82/230) | 41.1 (46/112) | 1.27 (0.78–2.07) | 0.34 |
| C. trachomatis test positive | 270 | 9.5 (18/189) | 19.8 (16/81) | 2.30 (1.06–5.00) | 0.035 |
| Genital warts present | 341 | 17.8 (41/230) | 12.6 (14/111) | 0.66 (0.34–1.31) | 0.24 |
| Symptomatic attendance at this clinic visit | 342 | 51.3 (118/230) | 63.4 (71/112) | 1.78 (1.09–2.92) | 0.021 |
| Self-referral to clinic at this visit | 333 | 83.9 (188/224) | 78.9 (86/109) | 0.60 (0.32–1.12) | 0.11 |
| Smoking | |||||
| Current smoker | 341 | 42.4 (97/229) | 57.1 (64/112) | 1.83 (1.13–2.96) | 0.013 |
| Alcohol use | |||||
| Six alcoholic drinks on one occasion once a week or more | 336 | 29.8 (67/225) | 29.7 (33/111) | 1.21 (0.72–2.03) | 0.48 |
| Consuming five or more drinks on a typical day of drinking | 331 | 57.7 (127/220) | 63.1 (70/111) | 1.12 (0.68–1.85) | 0.65 |
| Drink alcohol twice a week or more | 343 | 24.3 (56/230) | 31.9 (36/113) | 1.18 (0.70–2.0) | 0.54 |
*Adjusted for vaccination cohort.
CI, confidence interval; GUM, genitourinary medicine; OR, odds ratio; STI, sexually transmitted infection.