Percentages and trends of women reporting side effects with the use of different contraceptive methods in the two surveys conducted in 1993 and 2010
| Side effects | COC [n (%)] | p | DMPA [n (%)] | p | POP [n (%)] | p | Cu-IUD [n (%)] | p | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1993 (n=67) | 2010 (n=29) | 1993 (n=26) | 2010 (n=35) | 1993 (n=30) | 2010 (n=14) | 1993 (n=28) | 2010 (n=2) | |||||
| Woman-years of use | 148 | 98 | 44 | 77 | 77 | 53 | 140 | 7 | ||||
| Irregular bleeding | 3 (4.5) | 1 (3.4) | 0.817 | 8 (30.8) | 6 (20.0) | 0.009 | 6 (20.0) | 1 (7.1) | 0.278 | 0 | 1 (50.0) | |
| Forgetfulness, depression | 7 (10.4) | 4 (13.8) | 0.637 | 1 (3.8) | 1 (3.3) | 0 | 1 (3.3) | 0 | 0 | 0 | ||
| Amenorrhoea | 0 | 0 | 5 (19.2) | 1 (3.3) | 0.634 | 1 (3.3) | 0 | 0 | 0 | |||
| Menorrhagia | 2 (2.9) | 0 | 4 (15.4) | 0 | 0.016 | 0 | 0 | 11 (39.2) | 0 | 0.009 | ||
| Weight gain | 11 (16.4) | 0 | 0.020 | 0 | 3 (10.0) | 0.074 | 3 (10.0) | 2 (14.3) | 0.072 | 0 | 0 | |
| DVT, PE | 2 (2.9) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| Stroke | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||||
| Failure | 15 (22.4) | 1 (3.4) | 0.022 | 0 | 6 (21.4) | 6 (21.4) | 0 | 0.072 | 6 (21.4) | 0 | 0.464 | |
| Discontinuation due to side effects | 8 (12.0) | 2 (6.9) | 0.458 | 3 (11.6) | 2 (6.7) | 0.039 | 2 (6.7) | 0 | 0.323 | 0 | 0 | |
| Increased crises | 4 (5.9) | 1 (3.4) | 0.610 | 0 | 0 | 0 | 0 | 1 (3.5) | 0 | 0.786 | ||
COC, combined oral contraceptive pill; Cu-IUD, copper-containing intrauterine device; DMPA, depot medroxyprogesterone acetate; DVT, deep vein thrombosis; PE, pulmonary embolism.