Letters to the EditorFluorouracil and folinic acid in colon cancer
References (2)
- et al.
Levamisole and fluorouracil for adjuvant therapy of resected colon cancer
N Engl J Med
(1990) NIH Consensus Conference. Adjuvant therapy for patients with colon and rectal cancer
JAMA
(1990)
Cited by (11)
A phase III randomised trial of LV5FU2 + irinotecan versus LV5FU2 alone in adjuvant high-risk colon cancer (FNCLCC Accord02/FFCD9802)
2009, Annals of OncologyCitation Excerpt :These data provided a background to compare this new combination to the LV5FU2 regimen alone in the adjuvant setting. Considering the higher risk of toxicity, especially diarrhoea, of LV5FU + IRI given after primary tumour surgery, we chose to evaluate this regimen in a stage III population at a particularly high risk of recurrence defined by patients with more than three involved lymph nodes (N2) or N1 detected by perforation or occlusion [3, 8]. The FNCLCC/FFCD intergroup decided to conduct this adjuvant trial to evaluate the addition of irinotecan to LV5FU2 in terms of disease-free survival (DFS), OS and safety in stage III CRC patients at a high risk of relapse.
Clinicopathological predictors of benefit from adjuvant chemotherapy for stage C colorectal cancer: Microsatellite unstable cases benefit
2015, Asia-Pacific Journal of Clinical OncologyOutcome of functional end-to-end anastomosis following right hemicolectomy
2009, International Surgery
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