Abstract
Human papilloma virus is associated with a multitude of lower genital tract diseases in women in addition to cervical cancer, including genital warts, vulvar intraepithelial neoplasia, vaginal intraepithelial neoplasia, and some vulvar, vaginal, and anal cancers that are associated with oncogenic subtypes. The degree to which HPV manifests pathology depends on viral type, host immune response, and local environmental factors. This article reviews the evaluation and management of the following vulvar and vaginal human papilloma virus diseases: condyloma, vulvar intraepithelial neoplasia, and vaginal intraepithelial neoplasia. Included is a brief discussion of the association with vulvar and vaginal cancer.
Published by Elsevier Inc.
MeSH terms
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Adolescent
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Adult
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Aged
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Aminoquinolines / therapeutic use
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Antineoplastic Agents
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Carcinoma in Situ / diagnosis
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Carcinoma in Situ / therapy
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Carcinoma in Situ / virology
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Colposcopy
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Condylomata Acuminata / drug therapy
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Condylomata Acuminata / surgery
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Condylomata Acuminata / virology
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Female
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Human papillomavirus 11
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Human papillomavirus 6
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Humans
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Imiquimod
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Interferon Inducers
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Middle Aged
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Neoplasm Recurrence, Local
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Papillomavirus Infections* / drug therapy
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Papillomavirus Infections* / prevention & control
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Papillomavirus Infections* / surgery
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Papillomavirus Vaccines
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Podophyllotoxin / therapeutic use
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Pregnancy
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Pregnancy Complications, Infectious
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Sexually Transmitted Diseases / virology
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Trichloroacetic Acid / therapeutic use
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Vaginal Diseases / virology*
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Vaginal Neoplasms / diagnosis
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Vaginal Neoplasms / therapy
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Vaginal Neoplasms / virology
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Vaginal Smears
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Vulvar Diseases / virology*
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Vulvar Neoplasms / diagnosis
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Vulvar Neoplasms / therapy
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Vulvar Neoplasms / virology
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Young Adult
Substances
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Aminoquinolines
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Antineoplastic Agents
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Interferon Inducers
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Papillomavirus Vaccines
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Trichloroacetic Acid
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Podophyllotoxin
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Imiquimod