Chemotherapy has direct toxic effects on cancer cells; however, long-term cancer control
and complete remission are likely to involve CD8+ T cell immune responses. To study the …

Oncogenic metadherin is a key contributor to tumourigenesis with metadherin expression
and cytoplasmic localisation previously linked to poor survival. A number of reports have …

Advanced therapy medicinal products (ATMPs) are potential game changers in modern
medical care with an anticipated major impact for patients and society. They are a new drug …

5. Baeyens AAL, Schwab SR. Finding a way out: S1P signaling and immune cell migration.
Annu Rev Immunol. 2020; 38: 759-784. 6. Jaigirdar SA, Benson RA, Elmesmari A, et al …

Motivated by the recent implication of cysteine protease cathepsin L as a potential target for
anti-cancer drug development, we used a conditional MycERTAM; Bcl-xL model of …

Guessing occurs on forced-choice (FC) tests for which responses cannot be based on
relevant knowledge. Its importance is in inverse relation to the level of knowledge being …

Purpose: Neuroblastoma is a childhood malignancy originating from the sympathetic
nervous system with a complex biology, prone to metastasize and relapse. High-risk …

Maura Dandri1, Eckart Matthes2, Tassilo Volz1, Marc Lutgehetmann1, Joerg Petersen3;
1Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg …

How do organisms “know” when to stop growing? Why do our internal organs grow to a
characteristic size and shape? These are fundamental biological questions to which we still …

Premenstrual syndrome: a plea for greater understanding Page 1 PERSONAL VIEW Attitudes
by medical professionals, in particular male general practitioners (GPs) and gynaecologists …