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Another flawed database analysis of VTE risk and hormonal contraceptives
  1. Anne Szarewski, Editor-in-Chief1,
  2. Diana Mansour2
  1. Journal of Family Planning and Reproductive Health Care, and Clinical Senior Lecturer, Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine, Queen Mary, University of London, London, UK
  2. Consultant in Community Gynaecology and Reproductive Health Care, Head of Sexual Health Services, Newcastle upon Tyne, UK

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Ø Lidegaard, LH Nielson, CW Skovlund. Venous thrombosis in users of non-oral hormonal contraception: follow-up study, Denmark 2001–10. BMJ 2012;344:e2990

This is basically a companion paper to the one published last year in the British Medical Journal,1 which concentrated on the pill and was comprehensively criticised in the January 2012 issue of this Journal,2 to which readers are referred. This analysis, also from the Danish registry, looks at the Evra® patch, NuvaRing®, Implanon® and the levonorgestrel-releasing intrauterine system (Mirena® IUS). All the previous issues of confounding, lack of information regarding smoking, body mass index and family history, and not comparing like with like, apply here.

It is important to compare new users with new users, as a well-established fact is that the …

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Footnotes

  • Competing interests Anne Szarewski has received honoraria, consultancy fees and conference sponsorship from Bayer Schering (formerly Schering HealthCare), Schering Plough (formerly Organon), Janssen-Cilag and Wyeth. Diana Mansour has received honoraria, consultancy fees and conference sponsorship from Bayer Schering (formerly Schering HealthCare), Schering Plough (formerly Organon), Janssen-Cilag, HRA Pharma and Wyeth.

  • Provenance and peer review Not commissioned; internally peer reviewed.