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Contraceptive options for women with SLE: response to Mansour letter
  1. Kelly R Culwell, MD, MPH
  1. Kathryn M Curtis, PhD
  1. Assistant Professor and Director of Family Planning, Department of Obstetrics and Gynecology, University of California, Davis, CA, USA; kelly.culwell@ucdmc.ucdavis.edu
  2. Health Scientist, Division of Reproductive Health Centers for Disease Control and Prevention, Atlanta, GA, USA; kmc6@cdc.gov

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We thank Dr Mansour for her interest in our article1 and for her provocative questioning of the recommendations for use of progestogen-only contraceptives by women with systemic lupus erythematosus (SLE) who test positive for anti-phospholipid antibodies.2 We are sensitive to any reductions in choice of contraceptive methods, particularly for women in whom pregnancy has significant health consequences, such as women with SLE. As mentioned in our article, any considerations of contraceptive use in women with SLE must be weighed against the alternative of pregnancy, which brings many risks, particularly in women with active disease or those with positive anti-phospholipid antibodies.

We would first like to clarify an apparent misunderstanding by Dr Mansour that we believe that use of progestogen-only methods by women with SLE and positive anti-phospholipid antibodies is “unsafe”. The recommendations included in our article are those included in the World Health Organization (WHO) Medical Eligibility Criteria for Contraceptive …

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  • Competing interests None.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Authors’ note The findings and conclusions in this article are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.