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Journal review
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort study
  1. Sharon Cameron
  1. Consultant Gynaecologist, Chalmers Sexual and Reproductive Health Centre, Edinburgh, UK

https://doi.org/10.1136/jfprhc-2013-100616

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    Heffron R, Donnell D, Rees H, et al. Partners in Prevention HSV/HIV Transmission Study Team. Lancet Infect Dis 2012;12:19–26.

    This prospective cohort study examined use of hormonal contraceptives and risk of HIV-1 transmission amongst 3790 heterosexual couples in seven African countries who were discordant for HIV-1 and who were participating in two longitudinal studies over 2 years. Women were classed as either users of hormonal contraception (most common method was the injectable, 11%) or non-users (no method, condoms, sterilised). HIV-negative partners were tested for HIV every 3 months, and in those testing positive, DNA sequencing for HIV-1 was conducted to determine if the HIV …

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    Footnotes

    • Funding Sharon Cameron has received funding from Pfizer for research with Depo-Provera®.

    • Competing interests See Funding above.

    • Provenance and peer review Not commissioned; internally peer reviewed.