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Transmission of coronaviruses in utero appears minimal

The effect of the novel coronavirus SARS-CoV-2 (COVID-19) on pregnant women and infants has been a source of anxiety and confusion during the pandemic, with much conflicting evidence. A systematic review and meta-analysis, which includes data from 39 trials examining several types of coronavirus and associated syndromes (COVID-19, MERS, SARS), found a mortality rate of 2.7% among mothers and one-third admitted to the intensive care unit peripartum. The review also found no evidence of vertical (in utero) transmission to babies. However, as this review pooled data from studies examining COVID-19, MERS and SARS, its findings may not be directly applicable to the COVID-19 pandemic.

Eur J Med Res 2020;25:39.

Approximately 1-in-10 PrEP users purchase antibiotics to prevent STIs

Pre-exposure and postexposure prophylaxis (PrEP and PEP) for sexually transmitted infections (STIs) is a strategy that has had limited success in clinical trials and raises concerns of antimicrobial resistance. In recent years there has been growing awareness among clinicians that some patients are self-sourcing antibiotics to prevent STIs. This epidemiological study using an electronic survey among HIV PrEP users in the UK found that 9% reported purchasing antibiotics with the intention of preventing STIs. This behaviour was not limited geographically and was …

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  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient and public involvement Patients and/or the public were not involved in the design, or conduct, or reporting, or dissemination plans of this research.

  • Provenance and peer review Commissioned; internally peer reviewed.

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