PT  - JOURNAL ARTICLE
AU  - Kate Maclaran
AU  - Nick Panay
TI  - Premature ovarian failure
AID  - 10.1136/jfprhc.2010.0015
DP  - 2011 Jan 01
TA  - Journal of Family Planning and Reproductive Health Care
PG  - 35--42
VI  - 37
IP  - 1
4099  - http://jfprhc.bmj.com/content/37/1/35.short
4100  - http://jfprhc.bmj.com/content/37/1/35.full
SO  - J Fam Plann Reprod Health Care2011 Jan 01; 37
AB  - Premature ovarian failure (POF) is the occurrence of amenorrhoea, elevated gonadotrophins and hypoestrogenism in women under 40 years of age. It has important physical and psychological consequences and is increasingly common due to improved survival following treatment for malignancy. Despite this, it remains a poorly understood condition. Here we review the presentation and investigation of POF, discuss recent advances in the management of affected women, and suggest how our knowledge of the condition could be improved.