RT Journal Article SR Electronic T1 Age-related variation in sexual behaviours among heterosexual men residing in Brazil, Mexico and the USA JF Journal of Family Planning and Reproductive Health Care JO J Fam Plann Reprod Health Care FD British Medical Journal Publishing Group SP 261 OP 269 DO 10.1136/jfprhc-2012-100564 VO 40 IS 4 A1 August, Euna M A1 Daley, Ellen A1 Kromrey, Jeffrey A1 Baldwin, Julie A1 Romero-Daza, Nancy A1 Salmeron, Jorge A1 Lazcano-Ponce, Eduardo A1 Villa, Luisa L A1 Bryant, Carol A A1 Giuliano, Anna R YR 2014 UL http://jfprhc.bmj.com/content/40/4/261.abstract AB Objective To compare the prevalence of demographic characteristics and sexual behaviours across age groups and to estimate their significance in predicting sexual risk factors by age cohort. Methods This cohort study examined sexually transmitted infection (STI) prevalence among heterosexual men in Brazil, Mexico and the USA (N=3047). Participants completed a sexual risk factor questionnaire and were tested for chlamydia, gonorrhoea, syphilis and genital herpes. We examined sexual risk in the study population through a composite measure of STI positivity by age cohort (young: 18–30 years; middle-aged: 31–44 years; older: 45–70 years). Multivariable logistic regression models were used to generate adjusted odds ratios (AORs) and 95% confidence intervals (CIs). Results We found that STI positivity varied significantly by age group among heterosexual men by a number of covariates. In younger men, having more advanced education had a protective effect (16 years: AOR=0.37, 95% CI 0.15– 0.92), whereas higher numbers of sexual partners elevated the risk for STIs (20–49 partners: AOR=2.06, 95% CI 1.04–4.06; ≥50 partners: AOR=4.33, 95% CI 1.74–10.76). Middle-aged men who were black (AOR=1.64, 95% CI 1.10–2.42) and divorced/separated/widowed (AOR=1.91, 95% CI 1.21–3.02) had an increased risk for a positive STI test. Among older men, a younger age at first vaginal sexual encounter (AOR=3.75, 95% CI 1.45–9.74) and a history of exchanging sex for money or drugs heightened STI risk (AOR=2.30, 95% CI 1.0–5.04). Conclusions These findings demonstrate that age-related life experiences among heterosexual men influence sexual risk and STI transmission. This topic warrants further investigation to support the development and implementation of targeted interventions that may potentially reduce adverse sexual health outcomes.