PT - JOURNAL ARTICLE AU - Zeinab El-Dirani AU - Leen Farouki AU - Christelle Akl AU - Ubah Ali AU - Chaza Akik AU - Stephen J McCall TI - Factors associated with female genital mutilation: a systematic review and synthesis of national, regional and community-based studies AID - 10.1136/bmjsrh-2021-201399 DP - 2022 Mar 09 TA - BMJ Sexual & Reproductive Health PG - bmjsrh-2021-201399 4099 - http://jfprhc.bmj.com/content/early/2022/04/27/bmjsrh-2021-201399.short 4100 - http://jfprhc.bmj.com/content/early/2022/04/27/bmjsrh-2021-201399.full AB - Background This systematic review aimed to identify and describe the factors that influence female genital mutilation/cutting (FGM/C).Methods Searches were conducted in Medline, PsycInfo, Web of Science, Embase and the grey literature from 2009 to March 2020 with no language restrictions, using related MESH terms and keywords. Studies were included if they were quantitative and examined factors associated with FGM/C. Two researchers independently screened studies for inclusion, extracted data and assessed study quality. The direction, strength and consistency of the association were evaluated for determinants, presented as a descriptive summary, and were disaggregated by age and region.Results Of 2230 studies identified, 54 published articles were included. The majority of studies were from the African Region (n=29) followed by the Eastern Mediterranean Region (n=18). A lower level of maternal education, family history of FGM/C, or belonging to the Muslim religion (in certain contexts) increased the likelihood of FGM/C. The majority of studies that examined higher paternal education (for girls only) and living in an urban region showed a reduced likelihood of FGM/C, while conflicting evidence remained for wealth. Several studies reported that FGM/C literacy, and low community FGM/C prevalence were associated with a reduced likelihood of FGM/C.Conclusions There were several characteristics that appear to be associated with FGM/C, and these will better enable the targeting of policies and interventions. Importantly, parental education may be instrumental in enabling communities and countries to meet the Sustainable Development Goals.