Table 2

Results of depot medroxyprogesterone acetate versus intrauterine device for primary and secondary outcomes

OutcomeBaseline1-month follow-up3-month follow-up
DMPAIUDpDMPAIUDpDMPAIUDp
Depressionn=116n=118n=111n=117n=113n=117
Categorical data
 EPDS ≥962550.3627210.2720170.63
 EPDS ≥1235290.4113100.559100.93
 BDI-II ≥1422170.4434270.2530230.13
 BDI-II ≥29200.241170.39820.05
Continuous data [median (IQR)]
EPDS9 (3.0–21.0)8 (2.0–20.0)0.204 (1.0–18.0)2 (0–21.0)0.04*2 (0.5–19.0)2 (0–19.0)0.10
BDI-II6 (2.5–12.5)5 (2.0–11.5)0.108 (4.5–19.5)9 (4.5–14.5)0.209 (4.5–14.5)5 (2.0–11.5)0.002*
Sexual activityn=116n=118n=111n=117n=113n=117
 Resumption of sexual intercourseNANA14300.02†53 (111)64 (115)0.29
Menstruationn=110n=117n=110n=115
 NoneNANA64720.7032320.90
 Light flowNANA26230.5030190.07
 Heavy flowNANA450.908140.30
Dysmenorrhoean=56n=59n=84n=91
 Mild to severe painNANA9130.5016260.10
Infant feedingn=115n=116n=101n=109n=113n=116
 Breastmilk only90870.6060670.8047500.90
 Formula only14140.8024180.2034220.07
 Both11150.5017240.4032441.90
  • *p<0.05 (Wilcoxon test).

  • †Yates corrected Chi-square (χ2) test.

  • BDI, Beck Depression Inventory; DMPA, depot medroxyprogesterone acetate; EPDS, Edinburgh Postnatal Depression Scale; IQR, interquartile range; IUD, intrauterine device; NA, not applicable.