Antibiotic treatment at first presentation | First-line Mgen treatment once known Mgen-positive | Patients (n) | Returned for TOC (n) | TOC-positive | TOC-negative |
Doxycycline* | Azithromycin† | 43 | 28 | 17 | 11 |
Moxifloxacin‡ | 3 | 3 | 1 | 2 | |
Doxycycline§ | 1 | 0 | 0 | 0 | |
No treatment | 7 | 1 | 0 | 1 | |
Azithromycin¶ | Azithromycin† | 1 | 1 | 0 | 1 |
Moxifloxacin‡ | 2 | 2 | 0 | 2 | |
Doxycycline§ | 1 | 1 | 1 | 0 | |
Doxycycline+azithromycin** | Azithromycin† | 2 | 1 | 1 | 0 |
Moxifloxacin‡ | 0 | 0 | 0 | 0 | |
Ofloxacin+metronidazole†† | Azithromycin† | 8 | 4 | 0 | 4 |
Moxifloxacin‡ | 1 | 0 | 0 | 0 | |
No treatment | 1 | 0 | 0 | 0 | |
No antibiotic given | Azithromycin† | 17 | 9 | 5 | 4 |
Moxifloxacin‡ | 3 | 2 | 0 | 2 | |
No treatment | 2 | 0 | 0 | 0 | |
Other treatment including azithromycin | Azithromycin† | 7 | 3 | 1 | 2 |
Moxifloxacin‡ | 4 | 2 | 0 | 2 | |
No treatment | 1 | 0 | 0 | 0 | |
Other treatment | Azithromycin† | 5 | 3 | 1 | 2 |
Moxifloxacin‡ | 1 | 1 | 0 | 1 | |
Ofloxacin‡‡ | 1 | 1 | 0 | 1 | |
No treatment | 3 | 0 | 0 | 0 | |
Total | – | 114 | 62 | 27 | 35 |
*Doxycycline 100 mg BD 7–14 days.
†Azithromycin 500 mg stat then 250 mg OD for 4 days.
‡Moxifloxacin 400 mg OD 10–14 days.
§Doxycycline 100 mg BD for 7 days.
¶Azithromycin 1 g stat or 500 mg stat followed by 250 mg OD for 4 days.
**Azithromycin 1 g stat and doxycycline 100 mg BD 7 days.
††Oxfloxacin 400 mg BD for 14 days and metronidazole 400 mg BD for 5 days.
‡‡Oxfloxacin 200 mg BD for 14 days.
BD, twice a day; Mgen, Mycoplasma genitalium; OD, once a day; stat, immediately; TOC, test of cure.