Antibiotic | First-line treatment | First TOC | Second-line treatment | Second TOC | Third-line treatment | Third TOC | ||||||
n | % | Positive | Negative | n | % | Positive | Negative | n | % | Positive | Negative | |
Azithromycin* | 82 | 72 | 25 | 23 | 5 | 19 | 3 | 1 | – | – | – | – |
Doxycycline† | 2 | 2 | 1 | 0 | – | – | – | – | – | – | – | – |
Moxifloxacin‡ | 14 | 12 | 1 | 9 | 20 | 74 | 2 | 14 | 3 | 60 | 0 | 3 |
Azithromycin+metronidazole§ | 1 | 1 | 0 | 1 | – | – | – | – | – | – | – | – |
Ofloxacin¶ | 1 | 1 | 0 | 1 | – | – | – | – | – | – | – | – |
No treatment documented | 14 | 12 | 0 | 1 | 2 | 7 | 0 | 0 | 1 | 20 | 0 | 1 |
Pristinamycin+doxycycline** | – | – | – | – | – | – | – | – | 1 | 20 | 0 | 1 |
Total patients (n) | 114 | 100 | 27 | 35 | 27 | 100 | 5 | 15 | 5 | 100 | 0 | 5 |
*Azithromycin 500 mg stat followed by 250 mg OD for 4 days.
†Doxycycline 100 mg BD for 7 days.
‡Moxifloxacin 400 mg BD for 10–14 days.
§Azithromycin 500 mg stat followed by 250 mg OD for 4 days with metronidazole 400 mg BD for 5 days.
¶Ofloxacin 200 mg BD for 14 days.
**Pristinamycin 1 g QDS and doxycycline 100 mg BD for 10 days.
BD, twice a day; Mgen, Mycoplasma genitalium; OD, once a day; QDS, four times a day; stat, immediately; TOC, test of cure.