Route of misoprostol administration | Entire cohort (n=663) | Gestation under 10 weeks (n=642) | Gestation 10 weeks – 11 weeks and 6 days (n=21) |
Sublingual | 460 (69.4%) | 444 (69.2%) | 16 (76.2%) |
Vaginal | 170 (25.6%) | 166 (25.9%) | 4 (19.0%) |
Buccal | 1 (0.2%) | 1 (0.2%) | 0 |
Unknown | 32 (4.8%) | 31 (4.8%) | 1 (4.8%) |
Doses of misoprostol | Entire cohort (n=663) | Gestation under 10 weeks (n=642) | Gestation 10 weeks – 11 weeks and 6 days (n=21) |
800 μg dose only | 544 (82.1%) | 529 (82.4%) | 15 (71.4%) |
800 μg dose and 1×400 μg further dose | 89 (13.4%) | 84 (13.1%) | 5 (23.8%) |
800 μg dose and 2×400 μg further doses | 14 (2.1%) | 13 (2.0%) | 1 (4.8%) |
Unknown | 16 (2.4%) | 16 (2.5%) | 0 |
Used medications correctly?* | Entire cohort administering mifepristone (n=649) | Gestation under 10 weeks administering mifepristone (n=628) | Gestation 10 weeks – 11 weeks and 6 days administering mifepristone (n=21) |
Yes | 594 (91.5%) | 576 (91.7%) | 18 (85.7%) |
No | 52 (8.0%) | 49 (7.8%) | 3 (14.3%) |
Unknown | 3 (0.5%) | 3 (0.5%) | 0 |
Certain of pregnancy expulsion?† | Entire cohort (n=663) | Gestation under 10 weeks (n=642) | Gestation 10 weeks – 11 weeks and 6 days (n=21) |
Yes | 479 (72.2%) | 462 (72.0%) | 17 (81.0%) |
No or Not Sure | 161 (24.%) | 157 (24.5%) | 4 (19.0%) |
Unknown | 23 (3.5%) | 23 (3.6%) | 0 |
Induction–expulsion interval (hours)‡ | Entire cohort certain pregnancy expelled (n=479) | Gestation under 10 weeks certain pregnancy expelled (n=462) | Gestation 10 weeks – 11 weeks and 6 days certain pregnancy expelled (n=17) |
Mean | 4.3 | 4.3 | 4.4 |
Median | 3 | 3 | 2.5 |
SD | 4.3 | 4.3 | 4.2 |
Induction–expulsion interval (hours)§ | Cohort used medications correctly and certain pregnancy expelled (n=442) | Cohort used medications incorrectly and certain pregnancy expelled (n=37) | |
Mean | 4.2 | 5 | |
Median | 3 | 3.25 | |
SD | 4.2 | 5.3 |
*Correct use of mifepristone and misoprostol is defined as interval between mifepristone and misoprostol administration between 24 and 72 hours.
†Participants reporting they were certain that they had passed pregnancy tissue following misoprostol administration. ‘No’ means that they did not pass pregnancy, ‘Not sure’ means they do not know if they passed the pregnancy or not, ‘Unknown’ indicates the number of people not responding to the question.
‡ Misoprostol administration (induction) until expulsion of pregnancy intervals in hours, when participant was certain pregnancy expelled.
§Induction–expulsion interval when certain pregnancy expelled, grouped by correct or incorrect use of abortion medications.