Abstract
The use of the progestogen-only pill as a 'pre-coital contraceptive' was tested by in vitro studies of sperm-mucus interaction. The results suggest that a single tablet of levonorgestrel 30 microg, or norethisterone 350 microg, was effective in preventing sperm migration in the cervical mucus about 12 hours later. This suggests that the progestogen-only pill may be effective as a 'morning before pill'.
MeSH terms
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Cervix Mucus / drug effects*
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Contraceptives, Oral, Synthetic / administration & dosage
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Contraceptives, Oral, Synthetic / pharmacology*
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Female
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Humans
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Hydrogen-Ion Concentration / drug effects
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In Vitro Techniques
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Levonorgestrel / administration & dosage
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Levonorgestrel / pharmacology*
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Male
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Norethindrone / administration & dosage
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Norethindrone / pharmacology*
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Random Allocation
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Sperm Motility / drug effects*
Substances
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Contraceptives, Oral, Synthetic
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Levonorgestrel
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Norethindrone