User profiles for "author:Bettina Böttcher"

Bettina Böttcher

University of Würzburg
Verified email at uni-wuerzburg.de
Cited by 8822

[HTML][HTML] The gross structure of the respiratory complex I: a Lego System

T Friedrich, B Böttcher - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2004 - Elsevier
The proton-pumping NADH: ubiquinone oxidoreductase, also called complex I, is the entry
point for electrons into the respiratory chains of many bacteria and mitochondria of most …

Proteome organization in a genome-reduced bacterium

S Kühner, V van Noort, MJ Betts, A Leo-Macias… - Science, 2009 - science.org
The genome of Mycoplasma pneumoniae is among the smallest found in self-replicating
organisms. To study the basic principles of bacterial proteome organization, we used …

Native display of complete foreign protein domains on the surface of hepatitis B virus capsids

PA Kratz, B Böttcher, M Nassal - Proceedings of the …, 1999 - National Acad Sciences
The nucleocapsid of hepatitis B virus (HBV), or HBcAg, is a highly symmetric structure
formed by multiple dimers of a single core protein that contains potent T helper epitopes in …

[HTML][HTML] Impact of the opioid system on the reproductive axis

B Böttcher, B Seeber, G Leyendecker, L Wildt - Fertility and sterility, 2017 - Elsevier
Endogenous opioids, first described more than 40 years ago, have long been recognized for
their main role as important neuromodulators within the central nervous system. More …

Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit

T Schäfer, B Maco, E Petfalski, D Tollervey, B Böttcher… - Nature, 2006 - nature.com
The formation of eukaryotic ribosomes is a multistep process that takes place successively in
the nucleolar, nucleoplasmic and cytoplasmic compartments,,,. Along this pathway, multiple …

A conformational change in the adeno-associated virus type 2 capsid leads to the exposure of hidden VP1 N termini

S Kronenberg, B Böttcher, CW von der Lieth… - Journal of …, 2005 - Am Soc Microbiol
The complex infection process of parvoviruses is not well understood so far. An important
role has been attributed to a phospholipase A2 domain which is located within the unique N …

Proofreading of pre-40S ribosome maturation by a translation initiation factor and 60S subunits

S Lebaron, C Schneider, RW Van Nues… - Nature structural & …, 2012 - nature.com
In the final steps of yeast ribosome synthesis, immature translation-incompetent pre-40S
particles that contain 20S pre-rRNA are converted to the mature translation-competent …

[HTML][HTML] Mechanochemical removal of ribosome biogenesis factors from nascent 60S ribosomal subunits

C Ulbrich, M Diepholz, J Baßler, D Kressler, B Pertschy… - Cell, 2009 - cell.com
The dynein-related AAA ATPase Rea1 is a preribosomal factor that triggers an unknown
maturation step in 60S subunit biogenesis. Using electron microscopy, we show that Rea1's …

[HTML][HTML] Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsids

S Kronenberg, JA Kleinschmidt, B Böttcher - EMBO reports, 2001 - embopress.org
Adeno-associated virus type 2 empty capsids are composed of three proteins, VP1, VP2 and
VP3, which have relative molecular masses of 87, 72 and 62 kDa, respectively, and differ in …

[HTML][HTML] Cathelicidins have direct antiviral activity against respiratory syncytial virus in vitro and protective function in vivo in mice and humans

SM Currie, E Gwyer Findlay, AJ McFarlane… - The Journal of …, 2016 - journals.aai.org
Respiratory syncytial virus (RSV) is a leading cause of respiratory tract infection in infants,
causing significant morbidity and mortality. No vaccine or specific, effective treatment is …