Background Early adolescence (ages 10–14) is a period of increased expectations for boys
and girls to adhere to socially constructed and often stereotypical norms that perpetuate …

Perturbations in iron homeostasis and iron accumulation feature in several
neurodegenerative disorders including Alzheimer's disease (AD), Parkinson's disease (PD) …

Although acetaminophen (APAP) is usually considered as a safe drug, this painkiller can
lead to acute liver failure after overdoses. Moreover, there is evidence that the maximum …

Background Complement is likely to have a role in refractory generalised myasthenia gravis,
but no approved therapies specifically target this system. Results from a phase 2 study …

Background Iron content is increased in the substantia nigra of persons with Parkinson's
disease and may contribute to the pathophysiology of the disorder. Early research suggests …

Aims: The pathophysiological role of iron in Parkinson's disease (PD) was assessed by a
chelation strategy aimed at reducing oxidative damage associated with regional iron …

Parkinson's disease (PD) is a complex illness characterized by progressive dopaminergic
neuronal loss. Several mechanisms associated with the iron-induced death of dopaminergic …

Background: Severe gait disturbances and freezing episodes (frequently resistant to optimal
dopaminergic treatment) often appear in advanced Parkinson disease (PD). Even several …

Objectives To analyse the association between body mass index (BMI) and sexual activity,
sexual satisfaction, unintended pregnancies, and abortions in obese people and to discuss …

Depression is one of the most common psychiatric disturbances in Parkinson's disease
(PD). Recent reviews have highlighted the lack of controlled trials and the ensuing difficulty …