Iron deficiency (ID) is the most common micronutrient deficiency worldwide with> 20% of
women experiencing it during their reproductive lives. Hepcidin, a peptide hormone mostly …

A proliferation-inducing ligand (APRIL) promotes survival and drug resistance in multiple
myeloma (MM) cell lines. We studied the effect of APRIL on cell-cycle behavior in primary …

Defects in bone repair contribute to multiple myeloma (MM) bone disease. It is unknown
whether this reflects failure of osteogenic differentiation from mesenchymal stromal cells …

Objectives Bortezomib is an effective antimyeloma therapy, but clinical benefits can be
limited by neurotoxicity. In newly diagnosed, older patients, modification of the biweekly …

The use of consolidation or maintenance to improve disease response, and hence clinical
outcome, following autologous stem cell transplantation (ASCT) remains the subject of …

The article focuses on a study related to analysis of fluorescence in situ hybridization (FISH)
in relapsed myeloma patients. Topics discussed include an observed frequency of …

The paraprotein is an immunoglobulin produced at abnormally high levels by a clone of
plasma cells. These plasma cells may be relatively benign, with minimal proliferation and no …

The article comments on the importance of re-infused lymphocyte dose in the upfront
autologous stem cell transplantation (ASCT) for multiple myeloma. As stated, faster …

AM Schut participated in the design of the present study, helped to coordinate the study,
performed experiments, analysed and interpreted data and wrote the manuscript. A …

A welcome update of the UK Medical Eligibility Criteria (UKMEC) will be published in April
2016. 1 It continues the UKMEC's role of providing guidance on the safety of contraceptive …